TCS PrP Inhibitor 13

CAS No. 34320-83-7

TCS PrP Inhibitor 13 ( 5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One )

Catalog No. M27727 CAS No. 34320-83-7

TCS PrP Inhibitor 13 is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 46 Get Quote
5MG 72 Get Quote
10MG 115 Get Quote
25MG 260 Get Quote
50MG 410 Get Quote
100MG 605 Get Quote
500MG 1287 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    TCS PrP Inhibitor 13
  • Note
    Research use only, not for human use.
  • Brief Description
    TCS PrP Inhibitor 13 is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.
  • Description
    TCS PrP Inhibitor 13 is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.(In Vitro):In Schwannoma cells, administration of 0-500 μM TCS PrP Inhibitor 13 reduces levels of total ERK1/2, pAKT, total FAK, Cyclin D1, PrPC and increases expression of cleaved caspase-3 significantly. TCS PrP Inhibitor 13 also significantly reduces the number of proliferating, Ki67-positive cells and total cell number in Schwannoma cells.
  • Synonyms
    5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    34320-83-7
  • Formula Weight
    281.3
  • Molecular Formula
    C15H11N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    [O-][N+](=O)c1ccc(cc1)C1=NN(C(=O)C1)c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ensslin HK, Kovar KA, Maurer HH. Toxicological detection of the designer drug 3,4-methylenedioxyethylamphetamine (MDE, "Eve") and its metabolites in urine by gas chromatography-mass spectrometry and fluorescence polarization immunoassay. J Chromatogr B Biomed Appl. 1996 Aug 30;683(2):189-97.
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